SCHEMBL14695044

SCHEMBL14695044

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCSCC(=O)NCCNC(=O)Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.43
▸ ALOX12 P18054 3/20 0.42
▸ KDM4C Q9H3R0 2/20 0.42
▸ EPHX2 P34913 1/20 0.40
▸ CNR1 P21554 1/20 0.40
▸ CNR2 P34972 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ TRPV1 Q8NER1 1/20 0.39
▸ TRPM8 Q7Z2W7 1/20 0.39
▸ FAAH O00519 1/20 0.38
▸ PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14695046 1.00 MAPT (0.43) MAPTALOX12KDM4CEPHX2CNR1
SCHEMBL2229671 0.92 EPHX2 (0.46) MAPTALOX12KDM4CEPHX2CNR1
SCHEMBL2229680 0.92 EPHX2 (0.46) MAPTALOX12KDM4CEPHX2CNR1
SCHEMBL12518171 0.90 KDM4C (0.47) MAPTALOX12KDM4CCNR1CNR2
SCHEMBL14694859 0.90 KDM4C (0.47) MAPTALOX12KDM4CCNR1CNR2
SCHEMBL14695723 0.89 MAPT (0.40) MAPTALOX12KDM4CEPHX2CNR1
SCHEMBL12517948 0.89 MAPT (0.40) MAPTALOX12KDM4CEPHX2CNR1
SCHEMBL13540506 0.87 ALOX12 (0.55) MAPTALOX12KDM4CEPHX2CNR1
SCHEMBL14713105 0.85 ALDH1A1 (0.47) MAPTKDM4CEPHX2ALDH1A1
SCHEMBL14695199 0.84 KDM4C (0.44) MAPTALOX12KDM4CEPHX2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130046013-A1 SALICYLATE FATTY ACID DERIVATIVES HOVLAND RAGNAR (NO) 2013-02-21 — — US disclosed
US-20130046013-A1 SALICYLATE FATTY ACID DERIVATIVES HOVLAND RAGNAR (NO) 2013-02-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130046013-A1 SALICYLATE FATTY ACID DERIVATIVES FASN, SCD, FABP2 MAPT 4029/4885ALOX12 34/4885KDM4C 4019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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