SCHEMBL13540506

SCHEMBL13540506

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCNC(=O)Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALOX12 P18054 2/20 0.55
▸ CNR1 P21554 4/20 0.49
▸ ALDH1A1 P00352 3/20 0.49
▸ MAPT P10636 2/20 0.48
▸ KDM4C Q9H3R0 2/20 0.47
▸ FAAH O00519 1/20 0.46
▸ EPHX2 P34913 2/20 0.43
▸ CNR2 P34972 2/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ TRPV1 Q8NER1 1/20 0.41
▸ TRPM8 Q7Z2W7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5941246 0.89 CASR (0.49) ALOX12CNR1ALDH1A1MAPTFAAH
SCHEMBL17615841 0.88 ALOX12 (0.54) ALOX12CNR1ALDH1A1MAPTKDM4C
SCHEMBL455989 0.88 KDM4C (0.55) ALOX12CNR1ALDH1A1MAPTKDM4C
SCHEMBL469470 0.88 KDM4C (0.55) ALOX12CNR1ALDH1A1MAPTKDM4C
SCHEMBL14695046 0.87 MAPT (0.43) ALOX12CNR1ALDH1A1MAPTKDM4C
SCHEMBL14695044 0.87 MAPT (0.43) ALOX12CNR1ALDH1A1MAPTKDM4C
SCHEMBL1822294 0.87 ALDH1A1 (0.54) ALOX12CNR1ALDH1A1MAPTKDM4C
SCHEMBL1822295 0.87 ALDH1A1 (0.54) ALOX12CNR1ALDH1A1MAPTKDM4C
SCHEMBL13251770 0.87 KDM4C (0.51) ALOX12ALDH1A1MAPTKDM4CEPHX2
SCHEMBL13540681 0.86 ALOX12 (0.52) ALOX12CNR1ALDH1A1MAPTKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210169905-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. 2021-06-10 — — US disclosed
US-20200046738-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. 2020-02-13 — — US disclosed
EP-2813486-B1 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS INC (US) 2017-10-25 — — EP disclosed
US-20170246193-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. 2017-08-31 — — US disclosed
US-9708245-B2 Fatty acid acylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2017-07-18 — — US disclosed
US-9458094-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2016-10-04 — — US disclosed
US-9272984-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2016-03-01 — — US disclosed
US-9139516-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2015-09-22 — — US disclosed
US-9085527-B2 Fatty acid acylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2015-07-21 — — US disclosed
US-20150099723-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2015-04-09 — — US disclosed
EP-2813486-A1 Fatty acid acetylated salicylates and their uses Catabasis Pharmaceuticals, Inc. (US) 2014-12-17 — — EP disclosed
US-8846972-B2 — — 2014-09-30 — — US disclosed
US-20140221323-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2014-08-07 — — US disclosed
US-8735378-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2014-05-27 — — US disclosed
US-8735379-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2014-05-27 — — US disclosed
US-8729293-B2 Fatty acid acetylated salicylates and their uses CATABASIS PHARMACEUTICALS, INC. (US) 2014-05-20 — — US disclosed
WO-2010006085-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2010-01-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200046738-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 ALOX12 26/4885CNR1 984/4885ALDH1A1 285/4885
US-20150099723-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 ALOX12 26/4885CNR1 984/4885ALDH1A1 285/4885
US-20170246193-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 ALOX12 26/4885CNR1 984/4885ALDH1A1 285/4885
US-20140221323-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 ALOX12 26/4885CNR1 984/4885ALDH1A1 285/4885
US-20210169905-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 ALOX12 26/4885CNR1 984/4885ALDH1A1 285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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