Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 2/20 | 0.65 |
| ▸ | NNMT | P40261 | 2/20 | 0.61 |
| ▸ | AHCY | P23526 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.55 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.55 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.55 |
| ▸ | RNMT | O43148 | 1/20 | 0.55 |
| ▸ | INMT | O95050 | 1/20 | 0.55 |
| ▸ | TPMT | P51580 | 1/20 | 0.55 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.55 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14696483 | 1.00 | PRKACA (0.65) | PRKACANNMTAHCYHIF1ATMEM97 | |
| SCHEMBL14696726 | 0.96 | PRKACA (0.61) | PRKACANNMTAHCYHIF1ATMEM97 | |
| SCHEMBL11701602 | 0.93 | PRKACA (0.64) | PRKACANNMTAHCYHIF1ATMEM97 | |
| SCHEMBL11703275 | 0.92 | PRKACA (0.62) | PRKACANNMTAHCYHIF1ATMEM97 | |
| SCHEMBL11703639 | 0.89 | PRKACA (0.61) | PRKACANNMTAHCYHIF1ATMEM97 | |
| SCHEMBL7321542 | 0.86 | AHCY (0.62) | PRKACANNMTAHCYHIF1ATMEM97 | |
| SCHEMBL13487022 | 0.84 | NNMT (0.77) | PRKACANNMTAHCYHIF1ATMEM97 | |
| SCHEMBL14696727 | 0.83 | NNMT (0.78) | PRKACANNMTAHCYHIF1ATMEM97 | |
| SCHEMBL18026183 | 0.83 | EHMT1 (0.62) | AHCYDOT1LPRMT5EHMT1HSP90B1 | |
| SCHEMBL18026190 | 0.83 | EHMT1 (0.62) | AHCYDOT1LPRMT5EHMT1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174033-B2 | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2019-01-08 | — | — | US | disclosed |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174033-B2 | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | ADORA2A, ADORA3, ADORA1 | PRKACA 1274/4885NNMT 81/4885AHCY 217/4885 |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | ADORA2A, ADORA3, ADORA1 | PRKACA 1274/4885NNMT 81/4885AHCY 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.