SCHEMBL1469735

SCHEMBL1469735

CCOC(=O)CCN(C)CCCOc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.74
LSS P48449 3/20 0.58
ACHE P22303 6/20 0.57
BCHE P06276 5/20 0.57
PPARA Q07869 1/20 0.54
LMNA P02545 1/20 0.53
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12748152 0.91 LTA4H (0.62) LTA4HLSSACHEBCHEPPARA
SCHEMBL12748157 0.90 LTA4H (0.61) LTA4HLSSACHEBCHEPPARA
SCHEMBL12748065 0.90 LTA4H (0.61) LTA4HLSSACHEBCHEPPARA
SCHEMBL9772499 0.90 LTA4H (0.81) LTA4H
SCHEMBL1469807 0.87 LTA4H (0.76) LTA4HLSSACHEBCHEPPARA
SCHEMBL7139497 0.85 LTA4H (1.00) LTA4H
SCHEMBL12795298 0.85 LSS (0.58) LTA4HLSSACHEBCHEPPARA
SCHEMBL12748064 0.85 LTA4H (0.55) LTA4HLSSACHEBCHEPPARA
SCHEMBL13579103 0.84 ACHE (0.67) LTA4HLSSACHEBCHEPPARA
SCHEMBL25540208 0.84 LTA4H (0.73) LTA4HL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362101-B2 Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-01-29 US disclosed
US-8362101-B2 Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-01-29 US disclosed
US-8362101-B2 Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-01-29 US disclosed
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-24 US disclosed
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-24 US disclosed
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-24 US disclosed
WO-2009147054-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2009-12-10 WO disclosed
EP-2130818-A1 Multifunctional Type II photoinitiators and curable compositions AGFA Graphics NV (BE) 2009-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CRKL, CYTH2, CCNH LTA4H 507/4885LSS 1685/4885ACHE 3085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.