Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666210 | 0.84 | POLB (0.45) | POLBGAAHPGDALDH1A1KDM4E | |
| SCHEMBL2786923 | 0.83 | POLB (0.41) | POLBGAAHPGDALDH1A1KDM4E | |
| SCHEMBL14697610 | 0.82 | POLB (0.36) | POLBGAAHPGDALDH1A1KDM4E | |
| SCHEMBL14697698 | 0.81 | PTGS2 (0.41) | POLBPTGS2GAAHPGDALDH1A1 | |
| SCHEMBL4639194 | 0.77 | POLB (0.59) | POLBGAAHPGDALDH1A1KDM4E | |
| SCHEMBL4658270 | 0.76 | POLB (0.38) | POLBGAAHPGDALDH1A1KDM4E | |
| SCHEMBL2899052 | 0.76 | NPC1 (0.40) | POLBHPGDALDH1A1KDM4ENPC1 | |
| SCHEMBL14697609 | 0.74 | POLB (0.36) | POLBGAAHPGDALDH1A1KDM4E | |
| SCHEMBL2695475 | 0.74 | NPC1 (0.48) | POLBNPC1RAB9A | |
| SCHEMBL2900855 | 0.74 | POLB (0.36) | POLBGAAHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744784-A1 | CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013024170-A1 | CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2013-02-21 | — | — | WO | disclosed |