SCHEMBL14697698

SCHEMBL14697698

CONC(=O)c1cc(Cl)cc(C)c1N

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.41
ALDH1A1 P00352 7/20 0.40
GAA P10253 5/20 0.40
HPGD P15428 5/20 0.40
MAPT P10636 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 5/20 0.40
ABL1 P00519 1/20 0.39
SLC6A2 P23975 1/20 0.37
SLC6A3 Q01959 1/20 0.37
CYP3A4 P08684 1/20 0.36
GLA P06280 3/20 0.36
POLB P06746 1/20 0.35
ESR2 Q92731 1/20 0.35
BCL2L1 Q07817 1/20 0.35
LMNA P02545 2/20 0.35
FADS1 O60427 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27930599 0.83 ALDH1A1 (0.51) ALDH1A1GAAHPGDMAPTKDM4E
SCHEMBL1056378 0.83 ABL1 (0.53) ALDH1A1GAAHPGDMAPTHSD17B10
SCHEMBL384330 0.83 KDM4E (0.42) ALDH1A1GAAKDM4ECYP3A4GLA
SCHEMBL951324 0.83 ALDH1A1 (0.54) ALDH1A1GAAHPGDMAPTHSD17B10
SCHEMBL2489605 0.82 ALOX5 (0.46) ALDH1A1GAAHPGDKDM4E
Hydrochloric Acid SCHEMBL30808427 0.81 KDM4E (0.41) ALDH1A1GAAKDM4ECYP3A4GLA
SCHEMBL14697611 0.81 KDM4E (0.38) ALDH1A1GAAHPGDMAPTHSD17B10
SCHEMBL14697697 0.81 POLB (0.42) PTGS2ALDH1A1GAAHPGDMAPT
SCHEMBL2131841 0.79 POLB (0.47) ALDH1A1MAPTKDM4EPOLBBCL2L1
SCHEMBL12911919 0.79 KDM4E (0.39) ALDH1A1GAAMAPTHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2744784-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2014-06-25 EP disclosed
WO-2013024170-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2013-02-21 WO disclosed