Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1714983 | 1.00 | — | — | |
| Acetic Acid SCHEMBL30577413 | 0.92 | CA1 (0.31) | — | |
| Acetonitrile SCHEMBL3267900 | 0.88 | — | — | |
| Acetic Acid SCHEMBL985917 | 0.82 | CA1 (0.38) | — | |
| Acetic Acid SCHEMBL3783936 | 0.79 | FFAR3 (0.30) | — | |
| Acetic Acid SCHEMBL6353845 | 0.78 | — | — | |
| SCHEMBL30577408 | 0.76 | — | — | |
| Acetonitrile SCHEMBL985628 | 0.74 | — | — | |
| Acetonitrile SCHEMBL30588827 | 0.74 | — | — | |
| Acetic Acid SCHEMBL948383 | 0.72 | CA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328179-B2 | Water soluble norbornene-type polymers and photoimageable compositions thereof | PROMERUS, LLC (US) | 2016-05-03 | — | — | US | claimed |
| US-20140349233-A1 | WATER SOLUBLE NORBORNENE-TYPE POLYMERS AND PHOTOIMAGEABLE COMPOSITIONS THEREOF | SUMITOMO BAKELITE CO., LTD. (JP) | 2014-11-27 | — | — | US | claimed |
| EP-1973583-A1 | PREPARATION OF AN INORGANIC SUBSTRATE HAVING ANTIMICROBIAL PROPERTIES | Centre National de la Recherche Scientifique (FR) | 2008-10-01 | — | — | EP | claimed |
| WO-2007080291-A1 | PREPARATION OF AN INORGANIC SUBSTRATE HAVING ANTIMICROBIAL PROPERTIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-07-19 | — | — | WO | claimed |
| US-9328179-B2 | Water soluble norbornene-type polymers and photoimageable compositions thereof | PROMERUS, LLC (US) | 2016-05-03 | — | — | US | disclosed |
| US-8986923-B2 | Aqueous base-developable negative-tone films based on functionalized norbornene polymers | PROMERUS, LLC (US) | 2015-03-24 | — | — | US | disclosed |
| US-20140349233-A1 | WATER SOLUBLE NORBORNENE-TYPE POLYMERS AND PHOTOIMAGEABLE COMPOSITIONS THEREOF | SUMITOMO BAKELITE CO., LTD. (JP) | 2014-11-27 | — | — | US | disclosed |
| US-8765893-B2 | Norbornene-type polymers having quaternary ammonium functionality | PROMERUS, LLC (US) | 2014-07-01 | — | — | US | disclosed |
| US-20140038112-A1 | AQUEOUS BASE-DEVELOPABLE NEGATIVE-TONE FILMS BASED ON FUNCTIONALIZED NORBORNENE POLYMERS | PROMERUS, LLC (US) | 2014-02-06 | — | — | US | disclosed |
| US-8349858-B2 | Polycyclic guanine derivatives and use thereof | MERCK SHARP & DOHME (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120316176-A1 | DERIVATIVES OF 7,8-DIHYDRO-1H-IMIDAZO[2,1-b] PURIN-4(5H)-ONE and METHODS OF USE THEREOF | MERCK SHARP & DOHME CORP. | 2012-12-13 | — | — | US | disclosed |
| EP-1853972-B1 | NORBORNENE-TYPE POLYMERS AND THEIR MANUFACTURE PROCESS | PROMERUS LLC (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2031007-A2 | Norbornene-type polymers, compositions thereof and lithographic processes using such compositions | Promerus LLC (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1730773-B1 | POLYMERS OF POLYCYCLIC OLEFINS HAVING A POLYHEDRAL OLIGOSILSESQUIOXANE PENDANT GROUP AND USES THEREOF | PROMERUS LLC (US) | 2008-09-24 | — | — | EP | disclosed |
| US-20080124651-A1 | Method of controlling the differential dissolution rate of photoresist compositions, polycyclic olefin polymers and monomers used for making such polymers | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2008-05-29 | — | — | US | disclosed |
| EP-1730773-A1 | POLYMERS OF POLYCYCLIC OLEFINS HAVING A POLYHEDRAL OLIGOSILSESQUIOXANE PENDANT GROUP AND USES THEREOF | Promerus, LLC (US) | 2006-12-13 | — | — | EP | disclosed |
| US-20060234164-A1 | copolymerizing norbornene monomers containing ester groups, sulonamide groups, ethers, alcohols in presence of (Acetonitrile) bis(triisopropylphosphine)palladium(acetate) tetrakis (pentafluorophenyl)borate catalyst and an optional cocatalyst lithium tetrakis(pentafluorophenyl)borate diethyl etherate | PROMERUS LLC (US) | 2006-10-19 | — | — | US | disclosed |
| WO-2006091802-A2 | NORBORNENE-TYPE POLYMERS, COMPOSITIONS THEREOF AND LITHOGRAPHIC PROCESSES USING SUCH COMPOSITIONS | PROMERUS LLC (US) | 2006-08-31 | — | — | WO | disclosed |
| WO-2005081306-A1 | POLYMERS OF POLYCYCLIC OLEFINS HAVING A POLYHEDRAL OLIGOSILSESQUIOXANE PENDANT GROUP AND USES THEREOF | PROMERUS, LLC (US) | 2005-09-01 | — | — | WO | disclosed |
| US-20050192409-A1 | Polymers of polycyclic olefins having a polyhedral oligosilsesquioxane pendant group and uses thereof | PROMERUS, LLC | 2005-09-01 | — | — | US | disclosed |