Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | CRYAB | P02511 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PTGES | O14684 | 3/20 | 0.52 |
| ▸ | CRYAA | P02489 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lanosterol SCHEMBL3658283 | 0.83 | CRYAB (0.89) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL159792 | 0.80 | EBP (0.47) | ACLYACACAHMGCRPLA2G1B | |
| Lanosterol SCHEMBL17428540 | 0.79 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL18688634 | 0.79 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL288881 | 0.79 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL20225105 | 0.79 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL11914239 | 0.79 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL1952146 | 0.79 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL21348006 | 0.79 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| Lanosterol SCHEMBL15977092 | 0.79 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388316-B2 | Fouling-resistant composition comprising sterols and/or derivatives thereof | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2016-07-12 | — | — | US | disclosed |
| EP-2744856-A1 | FOULING-RESISTANT COMPOSITION COMPRISING STEROLS AND/OR DERIVATIVES THEREOF | Akzo Nobel Coatings International B.V. (NL) | 2014-06-25 | — | — | EP | disclosed |
| US-20140155530-A1 | FOULING-RESISTANT COMPOSITION COMPRISING STEROLS AND/OR DERIVATIVES THEREOF | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2014-06-05 | — | — | US | disclosed |
| WO-2013024106-A1 | FOULING-RESISTANT COMPOSITION COMPRISING STEROLS AND/OR DERIVATIVES THEREOF | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2013-02-21 | — | — | WO | disclosed |