SCHEMBL14698533

SCHEMBL14698533

CON=Cc1cc(C)c2nc(-c3cnn(CC(F)(F)F)c3-c3ncccc3Cl)oc(=O)c2c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ METAP2 P50579 2/20 0.32
▸ CNR1 P21554 1/20 0.31
▸ KLK7 P49862 1/20 0.30
▸ KLK14 Q9P0G3 1/20 0.30
▸ KLK5 Q9Y337 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14698532 1.00 METAP2 (0.32) METAP2CNR1KLK7KLK14KLK5
SCHEMBL14698109 0.86 METAP2 (0.36) METAP2CNR1KLK7KLK14KLK5
SCHEMBL14698538 0.81 C1R (0.33) KLK7KLK14KLK5
SCHEMBL14698537 0.81 C1R (0.33) KLK7KLK14KLK5
SCHEMBL14698293 0.71 MALT1 (0.34) —
SCHEMBL14698291 0.71 MALT1 (0.34) —
SCHEMBL16014835 0.70 — —
SCHEMBL17417209 0.70 — —
SCHEMBL14698498 0.68 TRPM5 (0.35) —
SCHEMBL14698499 0.68 TRPM5 (0.35) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140171316-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-19 — — US disclosed
EP-2742038-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-18 — — EP disclosed
WO-2013024006-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140171316-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES ANTXR2, NQO2, AAAS METAP2 975/4885CNR1 2035/4885KLK7 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback