Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12799797 | 0.81 | HTT (0.44) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL12445354 | 0.80 | HTT (0.46) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL14700588 | 0.77 | TUBB4A (0.50) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL5686212 | 0.77 | KDM4E (0.46) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL12445342 | 0.76 | ALDH1A1 (0.44) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL14700548 | 0.76 | HTT (0.42) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL13144070 | 0.76 | HTT (0.42) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL14700563 | 0.75 | MAPT (0.44) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL15430979 | 0.75 | HTT (0.41) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL6817528 | 0.74 | HTT (0.47) | HTTKDM4EHSD17B10TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040234-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE | FUJI ELECTRIC CO., LTD. (JP) | 2013-02-14 | — | — | US | disclosed |