SCHEMBL14701100

SCHEMBL14701100

O=C1CCCc2c1[nH]c1c(Cl)cc(Br)cc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
MAPT P10636 5/20 0.58
LMNA P02545 5/20 0.57
MAPK1 P28482 2/20 0.57
KDM4E B2RXH2 8/20 0.54
HSD17B10 Q99714 7/20 0.54
GAA P10253 1/20 0.50
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HPGD P15428 3/20 0.43
ALOX15 P16050 2/20 0.38
IKBKB O14920 1/20 0.38
USP2 O75604 1/20 0.38
TP53 P04637 1/20 0.38
MAPK10 P53779 1/20 0.38
DYRK1A Q13627 1/20 0.38
POLB P06746 1/20 0.36
BRD4 O60885 2/20 0.35
CCNB2 O95067 1/20 0.35
CDK1 P06493 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31721150 0.91 ALDH1A1 (0.47) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL2360274 0.85 KDM4E (0.60) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL31721162 0.84 ALDH1A1 (0.68) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL2358941 0.82 ALDH1A1 (0.51) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL2328327 0.82 KDM4E (0.56) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL2323041 0.79 ALDH1A1 (0.54) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL18813918 0.79 ALDH1A1 (0.54) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL31721152 0.78 HSD17B10 (0.51) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL12440431 0.75 KDM4E (0.48) ALDH1A1MAPTLMNAMAPK1KDM4E
SCHEMBL2359172 0.73 KDM4E (0.57) ALDH1A1MAPTLMNAMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025231227-A1 NEW COMPOUNDS FOR MEDICAL USE MOGLING BIO INC. (US) 2025-11-06 WO disclosed
US-8987319-B2 Selective androgen receptor modulators RADIUS HEALTH, INC. (US) 2015-03-24 US disclosed
US-8987319-B2 Selective androgen receptor modulators RADIUS HEALTH, INC. (US) 2015-03-24 US disclosed
US-20130041007-A1 Selective Androgen Receptor Modulators RADIUS HEALTH, INC. 2013-02-14 US disclosed
US-20130041007-A1 Selective Androgen Receptor Modulators RADIUS HEALTH, INC. 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041007-A1 Selective Androgen Receptor Modulators AR, SHBG, GPR119 ALDH1A1 1091/4885MAPT 2494/4885LMNA 1447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.