SCHEMBL14701259

SCHEMBL14701259

C=CC(=O)OCc1c2ccccc2c(O)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.45
HCAR2 Q8TDS4 1/20 0.37
TSHR P16473 6/20 0.36
ALDH1A1 P00352 5/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
CYP3A4 P08684 3/20 0.36
HSD17B10 Q99714 1/20 0.36
AKR1B10 O60218 2/20 0.36
AKR1B1 P15121 2/20 0.36
CA12 O43570 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
THRA P10827 1/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16271386 0.85 THRB (0.44) THRBHCAR2TSHRALDH1A1TP53
SCHEMBL14701266 0.84 THRB (0.46) THRBHCAR2TSHRALDH1A1TP53
SCHEMBL68439 0.82 EPHX1 (0.50) THRBHCAR2TSHRALDH1A1TP53
SCHEMBL29531071 0.82 EPHX1 (0.50) THRBHCAR2TSHRALDH1A1TP53
SCHEMBL14701283 0.81 THRB (0.41) THRBHCAR2TSHRALDH1A1TP53
SCHEMBL14701257 0.80 THRB (0.40) THRBHCAR2TSHRALDH1A1TP53
SCHEMBL2026532 0.78 KDM4E (0.53) THRBALDH1A1HIF1AHSD17B10LMNA
SCHEMBL14701272 0.76 THRB (0.37) THRBTSHRALDH1A1CYP3A4POLB
SCHEMBL18904514 0.75 MAPT (0.40) THRBTSHRALDH1A1KDM4EPOLB
SCHEMBL10451653 0.74 THRB (0.53) THRBHCAR2TSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040225-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-05-26 US disclosed
US-8999624-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-07 US disclosed
US-20150050601-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND PATTERN FORMING METHOD USING THEREOF GLOBALFOUNDRIES U.S. INC. 2015-02-19 US disclosed
US-8715907-B2 Developable bottom antireflective coating compositions for negative resists INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-06 US disclosed
US-20130040238-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-14 US disclosed