SCHEMBL14701266

SCHEMBL14701266

C=CC(=O)OCc1c2ccccc2c(C(=O)O)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
ALDH1A1 P00352 7/20 0.40
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
GLA P06280 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
HCAR2 Q8TDS4 1/20 0.38
LMNA P02545 1/20 0.36
TSHR P16473 5/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 3/20 0.34
AKT1 P31749 1/20 0.34
CA12 O43570 1/20 0.34
AKR1B10 O60218 1/20 0.34
AKR1B1 P15121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701259 0.84 THRB (0.45) THRBALDH1A1HSD17B10KDM4EHPGD
SCHEMBL16271386 0.83 THRB (0.44) THRBALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL29531071 0.79 EPHX1 (0.50) THRBALDH1A1HSD17B10KDM4EMEN1
SCHEMBL68439 0.79 EPHX1 (0.50) THRBALDH1A1HSD17B10KDM4EMEN1
SCHEMBL14701283 0.79 THRB (0.41) THRBALDH1A1HSD17B10HPGDHCAR2
SCHEMBL14701257 0.78 THRB (0.40) THRBALDH1A1HSD17B10HPGDCYP2C19
SCHEMBL18904512 0.77 POLB (0.40) THRBALDH1A1HSD17B10KDM4EMEN1
SCHEMBL29487374 0.76 THRB (0.41) THRBALDH1A1HSD17B10KDM4ECYP1A2
Methacrylic Acid SCHEMBL23451953 0.75 EPHX1 (0.43) THRBALDH1A1HSD17B10KDM4EMEN1
SCHEMBL34054 0.74 HCAR2 (0.65) THRBALDH1A1KMT2AHCAR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040225-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-05-26 US disclosed
US-8999624-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-07 US disclosed
US-20150050601-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND PATTERN FORMING METHOD USING THEREOF GLOBALFOUNDRIES U.S. INC. 2015-02-19 US disclosed
US-8715907-B2 Developable bottom antireflective coating compositions for negative resists INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-06 US disclosed
US-20130040238-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-14 US disclosed