SCHEMBL14701257

SCHEMBL14701257

C=CC(=O)OCc1c2ccccc2c(C(C)(C)O)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.40
TSHR P16473 6/20 0.33
ALDH1A1 P00352 6/20 0.33
CYP3A4 P08684 4/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
HPGD P15428 2/20 0.33
HCAR2 Q8TDS4 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRA P10827 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
EPHX1 P07099 1/20 0.30
RAD52 P43351 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701272 0.87 THRB (0.37) THRBTSHRALDH1A1CYP3A4CYP2C9
SCHEMBL16271386 0.82 THRB (0.44) THRBTSHRALDH1A1CYP3A4TP53
SCHEMBL14701259 0.80 THRB (0.45) THRBTSHRALDH1A1CYP3A4TP53
SCHEMBL14701266 0.78 THRB (0.46) THRBTSHRALDH1A1CYP3A4CYP2C19
SCHEMBL68439 0.76 EPHX1 (0.50) THRBTSHRALDH1A1CYP3A4CYP2C19
SCHEMBL29531071 0.76 EPHX1 (0.50) THRBTSHRALDH1A1CYP3A4CYP2C19
SCHEMBL14701283 0.75 THRB (0.41) THRBTSHRALDH1A1CYP3A4TP53
SCHEMBL14701285 0.75 ACE2 (0.42) THRBTSHRALDH1A1CYP3A4CYP2C9
Methacrylic Acid SCHEMBL23451953 0.71 EPHX1 (0.43) THRBTSHRALDH1A1CYP2C19HPGD
SCHEMBL14701275 0.71 THRB (0.35) THRBMAPK1SMN1; SMN2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040225-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-05-26 US disclosed
US-8999624-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-07 US disclosed
US-20150050601-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND PATTERN FORMING METHOD USING THEREOF GLOBALFOUNDRIES U.S. INC. 2015-02-19 US disclosed
US-8715907-B2 Developable bottom antireflective coating compositions for negative resists INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-06 US disclosed
US-20130040238-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-14 US disclosed