SCHEMBL14701285

SCHEMBL14701285

C=CC(=O)OCc1ccc(C(C)(C)O)c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.42
THRB P10828 6/20 0.38
THRA P10827 2/20 0.33
ELANE P08246 1/20 0.32
TSHR P16473 4/20 0.32
ALDH1A1 P00352 4/20 0.31
CYP3A4 P08684 3/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TGM2 P21980 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701278 0.87 THRB (0.35) ACE2THRBTHRAMAPK1
SCHEMBL7236743 0.83 THRB (0.44) THRBTHRATSHRALDH1A1CYP3A4
SCHEMBL12242602 0.80 THRB (0.38) THRBTGM2
SCHEMBL27421526 0.79 THRB (0.45) THRBTHRATSHRALDH1A1CYP3A4
SCHEMBL12332753 0.79 THRB (0.44) THRBTHRATSHRALDH1A1HCAR2
SCHEMBL24609573 0.79 THRB (0.43) THRBTSHRALDH1A1CYP3A4HCAR2
SCHEMBL10033659 0.77 EP300 (0.41) THRBTHRATSHRTGM2SMN1; SMN2
SCHEMBL1493625 0.76 THRB (0.43) THRBTHRATSHRALDH1A1CYP3A4
SCHEMBL14701257 0.75 THRB (0.40) THRBTHRATSHRALDH1A1CYP3A4
SCHEMBL14331155 0.74 THRB (0.38) THRBTHRAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040225-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-05-26 US disclosed
US-8999624-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-07 US disclosed
US-20150050601-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND PATTERN FORMING METHOD USING THEREOF GLOBALFOUNDRIES U.S. INC. 2015-02-19 US disclosed
US-8715907-B2 Developable bottom antireflective coating compositions for negative resists INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-06 US disclosed
US-20130040238-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-14 US disclosed