SCHEMBL14701609

SCHEMBL14701609

Cc1cc2c(=O)c3ccccc3oc2c(C)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.58
MAOA P21397 10/20 0.57
PTGS2 P35354 1/20 0.55
KDM4E B2RXH2 3/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
HSD17B10 Q99714 2/20 0.52
MEN1 O00255 1/20 0.52
PKM P14618 1/20 0.52
RECQL P46063 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.50
HPGD P15428 1/20 0.50
PGAM1 P18669 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM5A P29375 1/20 0.49
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24403683 0.84 MAOA (0.61) TTRMAOAPTGS2KDM4ECYP3A4
SCHEMBL15477688 0.84 MAOB (0.43) KDM4ECYP3A4MAPTHSD17B10MEN1
SCHEMBL9837091 0.79 MEN1 (0.70) TTRMAOAPTGS2KDM4ECYP3A4
SCHEMBL9836063 0.79 KDM4E (0.49) TTRMAOAPTGS2KDM4EMEN1
SCHEMBL24120562 0.78 PTGS2 (0.71) TTRMAOAPTGS2KDM4ECYP3A4
SCHEMBL9835933 0.78 PTGS2 (0.71) MAOAPTGS2KDM4ECYP3A4MAPT
SCHEMBL29398254 0.78 PTGS2 (0.57) TTRMAOAPTGS2KDM4ECYP3A4
SCHEMBL1324122 0.78 PTGS2 (0.57) TTRMAOAPTGS2KDM4ECYP3A4
SCHEMBL7253352 0.76 TTR (0.67) TTRMAOAPTGS2KDM4ECYP3A4
SCHEMBL29838129 0.76 TTR (0.67) TTRMAOAPTGS2KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318712-B2 Xanthone compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
US-20130214268-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-22 US disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed