Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14704027 | 0.81 | ALDH1A1 (0.47) | ALDH1A1NFE2L2SLC6A4MEN1KMT2A | |
| SCHEMBL14704047 | 0.81 | ALDH1A1 (0.47) | ALDH1A1NFE2L2SLC6A4MEN1KMT2A | |
| SCHEMBL105035 | 0.80 | ALDH1A3 (0.52) | ALDH1A1NFE2L2MEN1KMT2ANPSR1 | |
| SCHEMBL22878908 | 0.80 | ALDH1A1 (0.41) | ALDH1A1NFE2L2SLC6A4MEN1KMT2A | |
| SCHEMBL28771457 | 0.78 | ALDH1A1 (0.48) | ALDH1A1NFE2L2SLC6A4MEN1KMT2A | |
| SCHEMBL29619678 | 0.78 | ALDH1A1 (0.48) | ALDH1A1NFE2L2SLC6A4MEN1KMT2A | |
| SCHEMBL14701611 | 0.78 | CA1 (0.55) | ALDH1A1SLC6A4NPSR1LMNAMAPT | |
| SCHEMBL14701614 | 0.78 | ACHE (0.46) | ALDH1A1SLC6A4MEN1KMT2ANPSR1 | |
| SCHEMBL29619680 | 0.78 | ALDH1A1 (0.48) | ALDH1A1NFE2L2SLC6A4MEN1KMT2A | |
| SCHEMBL13240427 | 0.77 | ALDH1A1 (0.44) | ALDH1A1NFE2L2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284350-B2 | IAP BIR domain binding compounds | PHARMASCIENCE INC. (CA) | 2016-03-15 | — | — | US | disclosed |
| US-20130040892-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC. (CA) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040892-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC2, BIRC3 | ALDH1A1 4122/4885NFE2L2 2588/4885SLC6A4 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.