Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14674656 | 0.87 | PPARG (0.33) | PPARGPPARAGABRA1GABRB2CXCR4 | |
| SCHEMBL14674855 | 0.82 | GABRA1 (0.35) | PPARGPPARAGABRA1GABRB2CXCR4 | |
| SCHEMBL16374660 | 0.74 | CXCR4 (0.33) | PPARGPPARACXCR4ALOX5HDAC3 | |
| SCHEMBL15199009 | 0.73 | CA1 (0.44) | — | |
| SCHEMBL2834770 | 0.73 | TBXAS1 (0.31) | CXCR4 | |
| SCHEMBL15197274 | 0.72 | PPARG (0.33) | PPARGPPARAHDAC3HDAC2HDAC8 | |
| SCHEMBL14674925 | 0.71 | FOLH1 (0.34) | — | |
| SCHEMBL15198937 | 0.69 | CA1 (0.52) | — | |
| SCHEMBL15198936 | 0.69 | CA1 (0.46) | — | |
| SCHEMBL16374705 | 0.68 | FPR2 (0.35) | CXCR4HDAC3HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013022797-A1 | RADIOLABELED PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2013-02-14 | — | — | WO | disclosed |