Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16386313 | 0.82 | SYK (0.46) | SYKMEN1GAAKMT2AIDO1 | |
| SCHEMBL15745438 | 0.79 | MEN1 (0.48) | SYKMEN1GAAKMT2ACTSK | |
| SCHEMBL4960232 | 0.77 | SYK (0.45) | SYKMEN1GAAKMT2AIDO1 | |
| SCHEMBL9880619 | 0.76 | MEN1 (0.46) | SYKMEN1GAAKMT2ACTSK | |
| SCHEMBL9880621 | 0.76 | MEN1 (0.46) | SYKMEN1GAAKMT2ACTSK | |
| SCHEMBL14701896 | 0.73 | PPARG (0.50) | SYKMEN1GAAKMT2AIDO1 | |
| SCHEMBL27397174 | 0.72 | MEN1 (0.53) | SYKMEN1GAAKMT2ACTSK | |
| SCHEMBL15745442 | 0.72 | MEN1 (0.53) | SYKMEN1GAAKMT2ACTSK | |
| SCHEMBL4740872 | 0.72 | KMT2A (0.54) | SYKMEN1GAAKMT2ACTSK | |
| SCHEMBL288557 | 0.72 | KMT2A (0.54) | SYKMEN1GAAKMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002286-A1 | CHEMICAL PREPARATION OF UBIQUITIN THIOESTERS AND MODIFICATIONS THEREOF | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY | 2016-01-07 | — | — | US | disclosed |
| US-9175053-B2 | Chemical preparation of ubiquitin thioesters and modifications thereof | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2015-11-03 | — | — | US | disclosed |
| US-20130041132-A1 | CHEMICAL PREPARATION OF UBIQUITIN THIOESTERS AND MODIFICATIONS THEREOF | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002286-A1 | CHEMICAL PREPARATION OF UBIQUITIN THIOESTERS AND MODIFICATIONS THEREOF | OTUB1, USP28, PTMS | SYK 1742/4885MEN1 4013/4885GAA 1281/4885 |
| US-20130041132-A1 | CHEMICAL PREPARATION OF UBIQUITIN THIOESTERS AND MODIFICATIONS THEREOF | OTUB1, USP28, PTMS | SYK 1742/4885MEN1 4013/4885GAA 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.