SCHEMBL288557

SCHEMBL288557

CC(CNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
GAA P10253 1/20 0.54
CTSS P25774 5/20 0.45
CTSK P43235 5/20 0.45
CTSL P07711 1/20 0.45
CTSB P07858 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
SYK P43405 1/20 0.43
SERPINE1 P05121 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CYP2D6 P10635 1/20 0.39
PCSK9 Q8NBP7 1/20 0.39
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825590 1.00 KMT2A (0.54) KMT2AMEN1GAACTSSCTSK
SCHEMBL4740872 1.00 KMT2A (0.54) KMT2AMEN1GAACTSSCTSK
SCHEMBL22728173 0.86 MEN1 (0.47) KMT2AMEN1GAACTSSCTSK
SCHEMBL15745442 0.86 MEN1 (0.53) KMT2AMEN1GAACTSSCTSK
SCHEMBL27397174 0.86 MEN1 (0.53) KMT2AMEN1GAACTSSCTSK
SCHEMBL5018863 0.86 MEN1 (0.49) KMT2AMEN1GAACTSSCTSK
SCHEMBL18261706 0.84 MEN1 (0.58) KMT2AMEN1GAACTSSCTSK
SCHEMBL4766420 0.83 MEN1 (0.46) KMT2AMEN1GAACTSSCTSK
SCHEMBL7973701 0.83 MEN1 (0.45) KMT2AMEN1GAACTSSCTSK
SCHEMBL1262055 0.83 CA12 (0.46) KMT2AMEN1GAACTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 CN claimed
EP-3860657-A1 SUSTAINED DELIVERY OF ANGIOPOETIN-LIKE 3 POLYPEPTIDES Novartis AG (CH) 2021-08-11 EP claimed
CN-112770782-A Sustained delivery of angiopoietin-like 3 polypeptides 诺华股份有限公司 2021-05-07 CN claimed
WO-2020070675-A1 SUSTAINED DELIVERY OF ANGIOPOETIN-LIKE 3 POLYPEPTIDES NOVARTIS AG (CH) 2020-04-09 WO claimed
EP-3612233-A1 SUSTAINED RELEASE DELIVERY SYSTEMS COMPRISING TRACELESS LINKERS Novartis AG (CH) 2020-02-26 EP claimed
CN-110603060-A Sustained release delivery system comprising traceless linker 诺华股份有限公司 2019-12-20 CN claimed
WO-2018193408-A1 SUSTAINED RELEASE DELIVERY SYSTEMS COMPRISING TRACELESS LINKERS NOVARTIS AG (CH) 2018-10-25 WO claimed
EP-4736854-A2 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS Bristol-Myers Squibb Company (US) 2026-05-06 EP disclosed
EP-4514473-B1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL MYERS SQUIBB CO (US) 2026-02-18 EP disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-20260008780-A1 SUBSTITUTED 3,4-DIHYDROISOQUINOLIN-1(2H)-ONE DERIVATIVES AND RELATED USES NODTHERA LTD (GB) 2026-01-08 US disclosed
US-20250320183-A1 Modulators of BCL6 as Ligand Directed Degraders CELGENE CORPORATION (US) 2025-10-16 US disclosed
US-12433949-B2 Sustained release delivery systems comprising traceless linkers NOVARTIS AG (CH) 2025-10-07 US disclosed
US-4644008-A Perhydroindole-2-carboxylic acids as antihypertensives ADIR (FR) 1987-02-17 US disclosed
US-4622232-A L-aminodicarboxylic acid alkanes GENERAL FOODS CORPORATION (US) 1986-11-11 US disclosed
US-4616031-A Perhydroindole-2-carboxylic acids as antihypertensives ADIR (FR) 1986-10-07 US disclosed
US-4616030-A Perhydroindole-2-carboxylic acids as antihypertensives ADIR (FR) 1986-10-07 US disclosed
US-4616029-A Perhydromdole-2-carboxylic acids as antihypertensives ADIR (FR) 1986-10-07 US disclosed
US-4565819-A ENZYME INHIBITORS, HYPOTENSIVE AGENTS ADIR (FR) 1986-01-21 US disclosed
US-4508729-A Substituted iminodiacids, their preparation and pharmaceutical compositions containing them ADIR (FR) 1985-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 KMT2A 1052/4885MEN1 4664/4885GAA 2026/4885
US-12433949-B2 Sustained release delivery systems comprising traceless linkers ABCB11, ABCB1, GHRHR KMT2A 1725/4885MEN1 2713/4885GAA 1634/4885
US-20260008780-A1 SUBSTITUTED 3,4-DIHYDROISOQUINOLIN-1(2H)-ONE DERIVATIVES AND RELATED USES NOD1, NLRP3, CASP1 KMT2A 3161/4885MEN1 1374/4885GAA 4644/4885
US-20250320183-A1 Modulators of BCL6 as Ligand Directed Degraders BCL6, BCL6B, BCL3 KMT2A 365/4885MEN1 1223/4885GAA 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.