SCHEMBL147028

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5197037	0.84	FABP6 (0.48)	POLBALDH1A1SMN1; SMN2KDM4EKMT2A
	SCHEMBL29242322	0.83	MAPT (0.47)	ALDH1A1KMT2ATP53MAPT
	SCHEMBL16466424	0.82	BRD4 (0.53)	ALDH1A1SMN1; SMN2BRD4BRD2BRD3
	SCHEMBL22510482	0.81	POLB (0.50)	MGLLPOLBALDH1A1SMN1; SMN2KDM4E
	SCHEMBL17232456	0.81	MAPT (0.51)	MGLLPOLBALDH1A1SMN1; SMN2BRD4
	SCHEMBL220816	0.79	MGLL (0.44)	MGLLPOLBALDH1A1SMN1; SMN2KDM4E
	SCHEMBL29348733	0.79	MAPT (0.49)	POLBALDH1A1KDM4EBRD4BRD2
	SCHEMBL25660301	0.79	MGLL (0.49)	MGLLPOLBALDH1A1SMN1; SMN2KDM4E
	SCHEMBL252411	0.77	KMT2A (0.41)	POLBALDH1A1SMN1; SMN2KDM4EBRD4
	SCHEMBL14410400	0.77	FABP6 (0.51)	MGLLPOLBALDH1A1SMN1; SMN2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.