Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9230401 | 0.79 | LMNA (0.46) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL11543742 | 0.79 | TSHR (0.50) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL10431575 | 0.76 | ADRA1A (0.50) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL245252 | 0.75 | KDM4C (0.60) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL9405817 | 0.75 | LMNA (0.58) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| Hexanoate SCHEMBL3411762 | 0.75 | FFAR4 (0.65) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| Hexanoate SCHEMBL3412902 | 0.75 | FFAR4 (0.65) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL10874908 | 0.75 | FFAR4 (0.46) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| Octanoic Acid SCHEMBL3413790 | 0.75 | FFAR4 (0.65) | LMNAFFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL6267662 | 0.74 | ENPEP (0.45) | LMNAALDH1A1TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013021344-A1 | IMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | LUPIN LIMITED (IN) | 2013-02-14 | — | — | WO | disclosed |