SCHEMBL147076

SCHEMBL147076

C=C(C)C(=O)NC(C)(C)CC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
EPHX1 P07099 2/20 0.41
TGFBR1 P36897 1/20 0.34
HTT P42858 3/20 0.33
MAPT P10636 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
DUT P33316 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21251495 0.84 TGFBR1 (0.34) POLBEPHX1TGFBR1
SCHEMBL22768268 0.83 TGFBR1 (0.32) POLBTGFBR1
SCHEMBL19425988 0.82 POLB (0.46) POLBEPHX1HTTMAPTALDH1A1
SCHEMBL13435149 0.82 TGFBR1 (0.32) TGFBR1
SCHEMBL7611640 0.80 TGFBR1 (0.39) POLBTGFBR1ALDH1A1
SCHEMBL21612680 0.80 TGFBR1 (0.35) TGFBR1ALDH1A1
SCHEMBL9805999 0.80 EPHX1 (0.40) POLBEPHX1TGFBR1MAPTALDH1A1
SCHEMBL491400 0.78 TDP1 (0.35) TGFBR1ALDH1A1
SCHEMBL730664 0.78 TGFBR1 (0.34) TGFBR1ALDH1A1
SCHEMBL9408888 0.77 POLB (0.50) POLBEPHX1HTTMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344520-A Resin and preparation method and application thereof 燧伦科技(上海)有限责任公司 2024-07-16 CN claimed
US-20180333345-A1 NON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-11-22 US claimed
EP-3377547-A1 ON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP Investments LLC (US) 2018-09-26 EP claimed
EP-1378531-B1 Reactive hot-melt adhesive compositions with improved green strength ROHM & HAAS (US) 2011-01-19 EP claimed
EP-0556001-B1 Improvements in or relating to printing plates AGFA GEVAERT NV (BE) 1999-10-20 EP claimed
US-5698627-A AN AQUEOUS SOLUTION OF A COPOLYMER OF AN ACRYLAMIDE, A VINYL COMPOUND HAVING A CATIONIC GROUP AND ANOTHER UNSATURATED COMPOUND PREPARED IN THE PRESENCE OF A POLYHYDROXY COMPOUND; FREENESS; RETENTION; HIGH STRENGTH JAPAN PMC CORPORATION (JP) 1997-12-16 US claimed
US-5609987-A OLEOPHILIC TANNING SYNTHETIC RESIN DU PONT (U.K.) LIMITED (GB) 1997-03-11 US claimed
EP-0735186-A2 Additive for papermaking and process for papermaking JAPAN PMC CORPORATION (JP) 1996-10-02 EP claimed
EP-0556001-A1 Improvements in or relating to printing plates Du Pont (UK) Limited (GB) 1993-08-18 EP claimed
US-12365815-B2 Polishing liquid, polishing liquid set, polishing method, and defect suppression method RESONAC CORPORATION (JP) 2025-07-22 US disclosed
US-20250197548-A1 BIODEGRADABLE GRAFT POLYMERS BASF SE (DE) 2025-06-19 US disclosed
WO-2025111424-A1 PARTICULATE VINYLAMINE COMPOSITIONS AND METHOD OF MAKING SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) 2025-05-30 WO disclosed
WO-2025111425-A1 A METHOD OF PRODUCING VINYLAMINE-CONTAINING POLYMERS SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) 2025-05-30 WO disclosed
WO-2025111428-A1 METHOD FOR PRODUCTION OF VINYL CARBOXAMIDE CONTAINING POLYMERS IN PARTICULATE FORM SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH) 2025-05-30 WO disclosed
US-4889797-A CONTAINING HYDROPHILIC POLYMER TO DECEASE SPREADING FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US disclosed
EP-0227741-A4 MULTICOLOR IMAGES USING AN ELECTRON BEAM. GAF CORP (US) 1987-11-23 EP disclosed
EP-0227741-A1 MULTICOLOR IMAGES USING AN ELECTRON BEAM GAF CORPORATION (US) 1987-07-08 EP disclosed
US-4668598-A Multicolor images using an electron beam GAF CORPORATION (US) 1987-05-26 US disclosed
WO-1987000645-A1 MULTICOLOR IMAGES USING AN ELECTRON BEAM GAF CORPORATION (US) 1987-01-29 WO disclosed
US-4120725-A POLYMERS OF ACRYLIC AMIDES AND OF VINYL OR ALLYL ALCOHOLS, VINYL IMIDES OR AMIDES OR VINYL MORPHOLINE FUJI PHOTO FILM CO., LTD. (JP) 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197548-A1 BIODEGRADABLE GRAFT POLYMERS PCNA, ALOX12, FASN POLB 525/4885EPHX1 758/4885TGFBR1 1820/4885
US-20180333345-A1 NON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF C9, C5, C1S POLB 524/4885EPHX1 4471/4885TGFBR1 1413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.