SCHEMBL491400

SCHEMBL491400

C=C(C)C(=O)NC(C)(C)CN

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
TGFBR1 P36897 1/20 0.34
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL28161968 0.89 ALDH1A1 (0.38) TDP1ALDH1A1
Vinyl Ether SCHEMBL28166136 0.88
SCHEMBL3422991 0.85 ALDH1A1 (0.34) TDP1TGFBR1ALDH1A1
SCHEMBL7611640 0.80 TGFBR1 (0.39) TDP1TGFBR1KDM4EALDH1A1
SCHEMBL9805999 0.80 EPHX1 (0.40) TDP1TGFBR1KDM4EALDH1A1
SCHEMBL21612680 0.80 TGFBR1 (0.35) TDP1TGFBR1KDM4EALDH1A1
SCHEMBL11139937 0.79 TGFBR1 (0.32) TDP1TGFBR1
SCHEMBL147076 0.78 POLB (0.43) TGFBR1ALDH1A1
SCHEMBL730664 0.78 TGFBR1 (0.34) TGFBR1ALDH1A1
SCHEMBL27775514 0.77 KDM4E (0.33) TGFBR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8603709-B2 Polyurethane anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2013-12-10 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-20110318679-A1 POLYURETHANE ANTICURL BACKSIDE COATING (ACBC) PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-12-29 US claimed
US-8084110-B2 Glycoluril resin and polyol resin members XEROX CORPORATION (US) 2011-12-27 US claimed
US-8067139-B2 Resin mixture backing layer containing photoconductor XEROX CORPORATION (US) 2011-11-29 US claimed
EP-2237114-A1 Glycoluril resin and polyol resin members Xerox Corporation (US) 2010-10-06 EP claimed
US-20100248103-A1 RESIN MIXTURE BACKING LAYER CONTAINING PHOTOCONDUCTOR XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100248107-A1 GLYCOLURIL RESIN AND POLYOL RESIN MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100248108-A1 GLYCOLURIL RESIN AND POLYOL RESIN DUAL MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100221651-A1 EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2010-09-02 US claimed
EP-2224288-A2 Epoxy carboxyl resin mixture hole blocking layer photoconductors Xerox Corporation (US) 2010-09-01 EP claimed
EP-1148944-B1 SURFACE MODIFIED DIVINYLBENZENE RESIN HAVING A HEMOCOMPATIBLE COATING DOW GLOBAL TECHNOLOGIES INC (US) 2010-04-21 EP claimed
US-7579126-B2 Hole blocking layer containing photoconductors XEROX CORPORATION (US) 2009-08-25 US claimed
US-20080220350-A1 Hole blocking layer containing photoconductors XEROX CORPORATION 2008-09-11 US claimed
EP-1967907-A1 Hole Blocking Layer Containing Photoconductors Xerox Corporation (US) 2008-09-10 EP claimed
US-20070248813-A1 Imaging member having styrene XEROX CORPORATION (US) 2007-10-25 US claimed
EP-1147138-A1 HYDROPHILIC AMPHOLYTIC POLYMER The B.F. Goodrich Company (US) 2001-10-24 EP claimed
WO-2000039176-A1 HYDROPHILIC AMPHOLYTIC POLYMER THE B.F. GOODRICH COMPANY (US) 2000-07-06 WO claimed
EP-3515402-B1 (METH)ACRYLATE BASED RESIN BINDER COMPOSITION ROEHM AMERICA LLC (US) 2024-11-27 EP disclosed
EP-0326827-A1 Resin compositions and multilayered structures utilizing the same KURARAY CO., LTD. (JP) 1989-08-09 EP disclosed