Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 6/20 | 0.36 |
| ▸ | CD14 | P08571 | 6/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639310 | 0.69 | CALM1 (0.45) | — | |
| SCHEMBL15733506 | 0.69 | IDO1 (0.36) | TNKS2 | |
| SCHEMBL13686090 | 0.69 | TLR4 (0.38) | TLR4CD14LY96HTR2A | |
| SCHEMBL15734344 | 0.68 | NOS1 (0.33) | TNKS2HTR2A | |
| SCHEMBL3873166 | 0.68 | TLR4 (0.40) | TLR4CD14LY96TNKS2 | |
| SCHEMBL3908852 | 0.67 | HRH1 (0.47) | — | |
| SCHEMBL15209652 | 0.67 | CHRM2 (0.45) | — | |
| SCHEMBL15734988 | 0.67 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL17077608 | 0.66 | CALM1 (0.42) | — | |
| SCHEMBL15733976 | 0.66 | IDO1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915438-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7271259-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2007-09-18 | — | — | US | disclosed |