SCHEMBL3908852

SCHEMBL3908852

CO[Si](CCCc1ccncc1)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.47
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
LOXL2 Q9Y4K0 2/20 0.43
HRH4 Q9H3N8 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
NAAA Q02083 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
NPC1 O15118 1/20 0.39
KMT2A Q03164 1/20 0.39
GLA P06280 1/20 0.37
LMNA P02545 2/20 0.37
PGK1 P00558 1/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330048 0.88 LOXL2 (0.46) HRH1ALDH1A1KDM4ELOXL2HRH3
SCHEMBL1639310 0.87 CALM1 (0.45) ALDH1A1
SCHEMBL17077608 0.83 CALM1 (0.42) ALDH1A1
SCHEMBL16352360 0.83 ALDH1A1 (0.48) ALDH1A1KDM4ELOXL2KMT2ALMNA
SCHEMBL3911466 0.82 HRH1 (0.46) HRH1ALDH1A1KDM4ELOXL2HRH4
SCHEMBL2822247 0.82 IDO1 (0.45) ALDH1A1SIGMAR1KMT2A
SCHEMBL25242964 0.81 CALM1 (0.44) ALDH1A1KDM4ELMNA
SCHEMBL3917416 0.81 HRH1 (0.44) HRH1ALDH1A1KDM4ELOXL2HRH4
SCHEMBL5361401 0.80 CYP1A2 (0.43) HRH1ALDH1A1KMT2A
SCHEMBL1585117 0.80 CALM1 (0.58) ALDH1A1SIGMAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147730-A PLATINUM HALIDE AND GROUP 4 METAL HALIDE CATALYSTS ON POLYMERIC OR TEXACO INC. (US) 1979-04-03 US claimed
EP-4286331-A1 METHOD USING ADSORBENT Mitsui Mining & Smelting Co., Ltd. (JP) 2023-12-06 EP disclosed
EP-4286333-A1 POROUS BODY, ADSORPTIVE MATERIAL CONTAINING SAID POROUS BODY, AND METHOD FOR REMOVING METAL AND/OR METAL ION USING SAID ADSORPTIVE MATERIAL Mitsui Mining & Smelting Co., Ltd. (JP) 2023-12-06 EP disclosed
CN-116963998-A Porous body, adsorbent material comprising the porous body, and method for removing metal and/or metal ions using the adsorbent material 三井金属矿业株式会社 2023-10-27 CN disclosed
CN-116806208-A Column, adsorbent comprising the column, and method for removing metal and/or metal ions using the adsorbent 三井金属矿业株式会社 2023-09-26 CN disclosed
CN-116761782-A Method of using adsorbent material 三井金属矿业株式会社 2023-09-15 CN disclosed
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed
US-4147730-A PLATINUM HALIDE AND GROUP 4 METAL HALIDE CATALYSTS ON POLYMERIC OR TEXACO INC. (US) 1979-04-03 US disclosed