Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079468 | 0.82 | MAPT (0.51) | MAPTALDH1A1HPGDKDM4EPLA2G1B | |
| SCHEMBL12037438 | 0.82 | CYP2A6 (0.44) | MAPTALDH1A1HPGDKDM4EPLA2G1B | |
| SCHEMBL14707992 | 0.82 | HDAC3 (0.47) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL14707990 | 0.78 | HDAC3 (0.49) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL85865 | 0.78 | CA1 (0.50) | MAPTALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL18713935 | 0.77 | HDAC1 (0.58) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL21012240 | 0.74 | HDAC6 (0.49) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL13963595 | 0.74 | LMNA (0.49) | MAPTALDH1A1HPGDKDM4EPLA2G1B | |
| SCHEMBL16976360 | 0.74 | GABRA1 (0.43) | MAPTALDH1A1HPGDKDM4EPLA2G1B | |
| SCHEMBL6955587 | 0.74 | MAPT (0.43) | HDAC1HDAC6MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013023999-A1 | REGIOSELECTIVE CARBOXYLATION OF NONNATURAL SUBSTRATE COMPOUNDS USING DECARBOXYLASES | ACIB GMBH (AT) | 2013-02-21 | — | — | WO | disclosed |