Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217674 | 0.87 | TRPA1 (0.41) | TRPA1ATMALDH1A1ESR1ESR2 | |
| SCHEMBL6340796 | 0.83 | TRPA1 (0.43) | TRPA1ATMKMT2AALDH1A1ESR1 | |
| SCHEMBL6912198 | 0.78 | LMNA (0.38) | TRPA1ATMKMT2AALDH1A1MAPT | |
| SCHEMBL8388510 | 0.78 | TRPA1 (0.39) | TRPA1ATMALDH1A1 | |
| SCHEMBL9223934 | 0.76 | POLB (0.42) | ATMKMT2AALDH1A1HTR2AMAPT | |
| SCHEMBL28899876 | 0.76 | CNR1 (0.37) | TRPA1ATMALDH1A1TP53MAPK1 | |
| SCHEMBL28899781 | 0.76 | CNR1 (0.37) | TRPA1ATMALDH1A1TP53MAPK1 | |
| SCHEMBL28960092 | 0.76 | CNR1 (0.37) | TRPA1ATMALDH1A1TP53MAPK1 | |
| SCHEMBL9343766 | 0.75 | TRPA1 (0.38) | TRPA1ATMALDH1A1HTR2AHTR2C | |
| SCHEMBL852173 | 0.75 | TRPA1 (0.38) | TRPA1ATMALDH1A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039949-B | Method of producing silylalkoxymethyl halide | DOW CORNING TORAY CO LTD | 2015-05-06 | — | — | CN | disclosed |
| EP-1799694-B1 | METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE | DOW CORNING TORAY CO LTD (JP) | 2012-05-09 | — | — | EP | disclosed |
| US-7915439-B2 | Method of producing silylalkoxymethyl halide | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20090203932-A1 | Method of Producing Silylalkoxymethyl Halide | DOW CORNING TORAY CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-1799694-A1 | METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE | Dow Corning Toray Co., Ltd. (JP) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006040964-A1 | METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE | DOW CORNING TORAY CO., LTD. (JP) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203932-A1 | Method of Producing Silylalkoxymethyl Halide | CBR3, CBR1, HRH3 | TRPA1 1394/4885ATM 2237/4885KMT2A 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.