Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678709 | 0.83 | HRH3 (0.46) | HRH3MAPTKDM4EHSD11B1LPAR1 | |
| SCHEMBL14710263 | 0.82 | HRH3 (0.45) | HRH3P2RY1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL14712065 | 0.82 | HRH3 (0.45) | HRH3MAPTALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL4858551 | 0.79 | MAPT (0.55) | P2RY1MAPTALDH1A1KDM4EGFER | |
| SCHEMBL844453 | 0.78 | OPRM1 (0.53) | HRH3MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1464894 | 0.78 | CA12 (0.44) | HRH3P2RY1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL5674433 | 0.76 | CA12 (0.45) | P2RY1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL14712079 | 0.76 | HRH3 (0.49) | HRH3MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL14710297 | 0.76 | HSD11B1 (0.40) | HRH3P2RY1ALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL20601546 | 0.76 | OPRM1 (0.52) | HRH3P2RY1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |