Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464894 | 0.95 | CA12 (0.44) | HRH3APPCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL23163646 | 0.88 | HRH3 (0.47) | HRH3ESR2KDM4EMAPTESR1 | |
| SCHEMBL14710263 | 0.85 | HRH3 (0.45) | HRH3HSD11B1LPAR1 | |
| SCHEMBL14712065 | 0.85 | HRH3 (0.45) | HRH3MAPTHSD11B1LPAR1 | |
| SCHEMBL23164033 | 0.83 | ALDH1A1 (0.47) | CYP2C19CYP2C9CYP3A4POLBMAPT | |
| SCHEMBL14711330 | 0.83 | HRH3 (0.44) | HRH3KDM4EMAPTHSD11B1LPAR1 | |
| SCHEMBL17077055 | 0.82 | OPRM1 (0.56) | — | |
| SCHEMBL844453 | 0.80 | OPRM1 (0.53) | HRH3CYP2C19CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL29143486 | 0.80 | ALDH1A1 (0.42) | HRH3HSD11B1LPAR1 | |
| SCHEMBL25315241 | 0.79 | CA12 (0.40) | HRH3CYP2C19CYP2C9CYP3A4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925059-A | Novel isoxazole FXR agonist, preparation method thereof and application thereof as medicine | 广东药科大学 | 2023-10-24 | — | — | CN | disclosed |
| US-20150259295-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS LPAR ANTAGONISTS | HOFFMANN-LA ROCHE INC. | 2015-09-17 | — | — | US | disclosed |
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
| EP-1764075-A1 | TISSUE FACTOR PRODUCTION INHIBITOR | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | HRH3 2474/4885APP 99/4885CYP2C19 2637/4885 |
| US-20150259295-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS LPAR ANTAGONISTS | LPAR3, LPAR1, LPAR2 | HRH3 479/4885APP 4221/4885CYP2C19 1876/4885 |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | HRH3 527/4885APP 1870/4885CYP2C19 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.