Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836934 | 0.88 | ACHE (0.38) | ALDH1A1NISCH | |
| SCHEMBL1116107 | 0.86 | ACHE (0.36) | NISCH | |
| SCHEMBL13712586 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRNISCH | |
| SCHEMBL3365487 | 0.76 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL8927323 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRNISCH | |
| SCHEMBL16406860 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRNISCH | |
| SCHEMBL174956 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRNISCH | |
| SCHEMBL17409158 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRNISCH | |
| SCHEMBL17358866 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRNISCH | |
| SCHEMBL6950285 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TSHRNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130042918-A1 | OLIGOTHIOPHENES | NR0B2, NR2C2, NR1H2 | ALDH1A1 1604/4885TSHR 63/4885NISCH 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.