Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934999 | 0.82 | CA2 (0.42) | SLC6A2SLC6A4SLC6A3CA2CA12 | |
| SCHEMBL1045835 | 0.78 | CA2 (0.38) | CA2CA12CA4CA6CA5A | |
| SCHEMBL29875658 | 0.78 | CA2 (0.38) | CA2CA12CA4CA6CA5A | |
| SCHEMBL866022 | 0.78 | MEN1 (0.44) | SLC6A2SLC6A4SLC6A3CA2CA12 | |
| SCHEMBL29803246 | 0.78 | MEN1 (0.44) | SLC6A2SLC6A4SLC6A3CA2CA12 | |
| SCHEMBL14899824 | 0.77 | NOS3 (0.42) | SLC6A2SLC6A4CA2GAAMEN1 | |
| Hydrochloric Acid SCHEMBL866021 | 0.76 | MEN1 (0.43) | SLC6A2SLC6A4SLC6A3CA2CA12 | |
| Fluoride SCHEMBL28825920 | 0.76 | CYP3A4 (0.43) | SLC6A2SLC6A4SLC6A3CA2CA12 | |
| Hydrochloric Acid SCHEMBL30932769 | 0.76 | MEN1 (0.43) | SLC6A2SLC6A4SLC6A3CA2CA12 | |
| Hydrochloric Acid SCHEMBL27724765 | 0.76 | MEN1 (0.43) | SLC6A2SLC6A4SLC6A3CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025078984-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AS KRAS DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-04-17 | — | — | WO | disclosed |
| US-8962670-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8962670-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8637490-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8637490-B2 | Anti-cancer agents | UWM RESEARCH FOUNDATION, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130045949-A1 | ANTI-CANCER AGENTS | UWM RESEARCH FOUNDATION, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-20130045949-A1 | ANTI-CANCER AGENTS | UWM RESEARCH FOUNDATION, INC. (US) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045949-A1 | ANTI-CANCER AGENTS | TP53, MCL1, HRAS | SLC6A2 4803/4885SLC6A4 4702/4885SLC6A3 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.