SCHEMBL866022

SCHEMBL866022

Nc1ccc(CO)cc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
SLC6A2 P23975 5/20 0.40
SLC6A4 P31645 5/20 0.40
CYP3A4 P08684 3/20 0.40
ALOX15 P16050 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
SLC6A3 Q01959 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
TP53 P04637 1/20 0.40
THRB P10828 1/20 0.40
CA12 O43570 2/20 0.39
CA2 P00918 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29803246 1.00 MEN1 (0.44) MEN1KMT2AKDM4EPOLBGAA
Hydrochloric Acid SCHEMBL866021 0.97 MEN1 (0.43) MEN1KMT2AKDM4EPOLBGAA
Hydrochloric Acid SCHEMBL27724765 0.97 MEN1 (0.43) MEN1KMT2AKDM4EPOLBGAA
Fluoride SCHEMBL28825920 0.97 CYP3A4 (0.43) MEN1KMT2AKDM4EPOLBGAA
Hydrochloric Acid SCHEMBL30932769 0.97 MEN1 (0.43) MEN1KMT2AKDM4EPOLBGAA
SCHEMBL12633800 0.86 GAA (0.54) MEN1KMT2AKDM4EPOLBGAA
SCHEMBL4021905 0.80 ALDH1A1 (0.52) MEN1KMT2AKDM4EPOLBGAA
SCHEMBL4720461 0.80 ALDH1A1 (0.52) MEN1KMT2AKDM4EPOLBGAA
SCHEMBL31061730 0.80 EGFR (0.43) MEN1KMT2AKDM4EPOLBGAA
SCHEMBL2342680 0.80 KDM4E (0.71) MEN1KMT2AKDM4EPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN claimed
CN-117051587-A Preparation process of washable efficient antibacterial polyester fabric 潮州市丹辉婚纱礼服有限公司 2023-11-14 CN claimed
CN-114805805-A Polyimide with high bonding strength and preparation method and application thereof 中国科学院深圳先进技术研究院 2022-07-29 CN claimed
CN-110437435-B One-step synthesis method of terminal amino-functionalized polyether 华南理工大学 2021-08-10 CN claimed
CN-110437435-A A kind of one-step method for synthesizing of terminal amino group functional polyethers UNIV SOUTH CHINA TECH 2019-11-12 CN claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
EP-4493638-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-01-22 EP disclosed
US-20240025861-A1 METHODS OF COUPLING A CARBON CONTAINING MOIETY TO AN AMINE CONTAINING MOIETY PURDUE RESEARCH FOUNDATION 2024-01-25 US disclosed
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN disclosed
CN-117051587-A Preparation process of washable efficient antibacterial polyester fabric 潮州市丹辉婚纱礼服有限公司 2023-11-14 CN disclosed
US-11787770-B2 Methods of coupling a carbon containing moiety to an amine containing moiety PURDUE RESEARCH FOUNDATION (US) 2023-10-17 US disclosed
US-4196125-A VIRICIDES ELI LILLY AND COMPANY (US) 1980-04-01 US disclosed
US-4179505-A ANTIALLERGENS; ANTIHISTAMINES JANSSEN PHARMACEUTICA N.V. (BE) 1979-12-18 US disclosed
US-4174454-A VIRICIDES ELI LILLY AND COMPANY (US) 1979-11-13 US disclosed
US-4150028-A Antiviral thiazolinyl benzimidazoles ELI LILLY AND COMPANY (US) 1979-04-17 US disclosed
US-4118573-A ANTIVIRAL AGENTS ELI LILLY AND COMPANY (US) 1978-10-03 US disclosed
US-4118742-A VIRICIDES ELI LILLY AND COMPANY (US) 1978-10-03 US disclosed
US-4018790-A VIRICIDES ELI LILLY AND COMPANY (US) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787770-B2 Methods of coupling a carbon containing moiety to an amine containing moiety HCCS, PAICS, PNMT MEN1 510/4885KMT2A 1256/4885KDM4E 2156/4885
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 MEN1 3530/4885KMT2A 558/4885KDM4E 844/4885
US-20240025861-A1 METHODS OF COUPLING A CARBON CONTAINING MOIETY TO AN AMINE CONTAINING MOIETY HCCS, PAICS, PNMT MEN1 510/4885KMT2A 1256/4885KDM4E 2156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.