Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14714512 | 0.87 | HPGDS (0.66) | HPGDSALDH1A1CYP3A4RAB9ANPC1 | |
| SCHEMBL9459921 | 0.83 | GAA (0.59) | ALDH1A1CYP3A4RAB9AGAALMNA | |
| SCHEMBL6365450 | 0.81 | CYP3A4 (0.47) | HPGDSALDH1A1CYP3A4RAB9ANPC1 | |
| SCHEMBL14724516 | 0.80 | RAB9A (0.58) | HPGDSALDH1A1CYP3A4RAB9ANPC1 | |
| SCHEMBL4067128 | 0.80 | ALDH1A1 (0.71) | HPGDSALDH1A1CYP3A4RAB9ANPC1 | |
| SCHEMBL1109093 | 0.79 | NPC1 (0.54) | HPGDSALDH1A1CYP3A4RAB9ANPC1 | |
| SCHEMBL12055633 | 0.79 | NPC1 (0.54) | HPGDSALDH1A1CYP3A4RAB9ANPC1 | |
| SCHEMBL1109199 | 0.79 | CYP26A1 (0.59) | HPGDSALDH1A1CYP3A4RAB9ANPC1 | |
| SCHEMBL2493020 | 0.79 | GAA (0.55) | ALDH1A1CYP3A4RAB9AGAALMNA | |
| SCHEMBL14755268 | 0.78 | CYP26A1 (0.58) | HPGDSALDH1A1CYP3A4RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562155-B1 | HYDROXAMIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2019-06-05 | — | — | EP | disclosed |
| EP-2562155-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-02-27 | — | — | EP | disclosed |