SCHEMBL147147

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14417384	0.78	HPGD (0.56)	KDM4EALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL20067689	0.78	ESR2 (0.46)	KDM4EALDH1A1NR1I2CASRNPC1
	SCHEMBL13250782	0.78	ESRRG (0.41)	KDM4EALDH1A1ESRRGCYP1A1CYP1A2
	SCHEMBL14817183	0.76	NPC1 (0.39)	ALDH1A1NPC1RAB9AHSD17B10ESR1
	SCHEMBL20724782	0.76	ESR2 (0.49)	ALDH1A1NPC1HSD17B10ESR1ESR2
	SCHEMBL266586	0.76	ESR2 (0.49)	ALDH1A1JAK2NPC1RAB9AHSD17B10
	SCHEMBL20067758	0.76	ALDH1A1 (0.41)	KDM4EALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL28831426	0.75	ESRRG (0.42)	KDM4EALDH1A1ESRRGCYP1A1CYP1A2
	SCHEMBL26841446	0.75	ALDH1A1 (0.40)	KDM4EALDH1A1CYP1A2NPC1RAB9A
	SCHEMBL11896137	0.75	ALDH1A1 (0.48)	KDM4EALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.