SCHEMBL14715162

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28317169	0.93	LMNA (0.68)	LMNAALDH1A1GAATSHRMAPT
	SCHEMBL14789085	0.89	LMNA (0.64)	LMNAALDH1A1GAATSHRMAPT
	1,6-Hexanediol SCHEMBL9543296	0.86	LMNA (0.64)	LMNAALDH1A1GAATSHRMAPT
	SCHEMBL14724487	0.85	GAA (0.55)	LMNAALDH1A1GAATSHRMAPT
	SCHEMBL14714485	0.84	PLA2G4B (0.55)	LMNAALDH1A1MAPTPOLBNPSR1
	SCHEMBL14724583	0.83	MAPT (0.50)	LMNAALDH1A1GAATSHRMAPT
	SCHEMBL28335565	0.81	LMNA (0.69)	LMNAALDH1A1GAATSHRMAPT
	SCHEMBL1587028	0.81	LMNA (0.54)	LMNAALDH1A1GAATSHRMAPT
	SCHEMBL1587023	0.81	LMNA (0.54)	LMNAALDH1A1GAATSHRMAPT
	SCHEMBL1587026	0.81	LMNA (0.54)	LMNAALDH1A1GAATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.