Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715162 | 0.83 | LMNA (0.61) | MAPTALDH1A1LMNAGAATSHR | |
| SCHEMBL14724487 | 0.80 | GAA (0.55) | MAPTALDH1A1LMNAGAATSHR | |
| SCHEMBL28335563 | 0.76 | MAPT (0.64) | MAPTALDH1A1LMNAGAATSHR | |
| SCHEMBL69268 | 0.75 | PTPN11 (0.69) | MAPTALDH1A1TSHRRAB9APTPN11 | |
| SCHEMBL28317169 | 0.75 | LMNA (0.68) | MAPTALDH1A1LMNAGAATSHR | |
| SCHEMBL25334000 | 0.74 | MAPT (0.66) | MAPTALDH1A1LMNAGAATSHR | |
| SCHEMBL20252721 | 0.74 | CA1 (0.60) | MAPTALDH1A1TSHRRAB9APTPN11 | |
| SCHEMBL14724525 | 0.74 | PKM (0.42) | TSHRPTPN11ACACB | |
| SCHEMBL20765902 | 0.73 | MAPT (0.68) | MAPTALDH1A1LMNAGAATSHR | |
| SCHEMBL2262978 | 0.72 | MAPT (0.58) | MAPTALDH1A1LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562155-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-02-27 | — | — | EP | disclosed |