Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715262 | 0.95 | ADRA1A (0.56) | ADRA1AADRA1B | |
| SCHEMBL14715408 | 0.91 | ADRA1A (0.50) | ADRA1AADRA1B | |
| SCHEMBL14715477 | 0.91 | ADRA1A (0.49) | ADRA1AADRA1B | |
| SCHEMBL14715396 | 0.90 | ADRA1A (0.50) | ADRA1AADRA1B | |
| SCHEMBL14715512 | 0.89 | ADRA1A (0.51) | ADRA1AADRA1B | |
| SCHEMBL2171759 | 0.88 | ADRA1A (0.53) | ADRA1AADRA1B | |
| SCHEMBL14715297 | 0.87 | ADRA1A (0.54) | ADRA1AADRA1B | |
| SCHEMBL14715409 | 0.87 | ADRA1A (0.57) | ADRA1AADRA1B | |
| SCHEMBL14715376 | 0.86 | WHR1 (0.46) | ADRA1AADRA1B | |
| SCHEMBL14715392 | 0.84 | WHR1 (0.44) | ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346848-B1 | QUINAZOLINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |