SCHEMBL14715334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14715017	0.86	HPGD (0.55)	NPC1RAB9AHSD17B10LMNAMAPT
	SCHEMBL14715050	0.83	NPC1 (0.41)	NPC1RAB9ATP53SMN1; SMN2ALDH1A1
	SCHEMBL14715049	0.82	PPARG (0.51)	PPARGHRH3
	SCHEMBL14714539	0.81	HPGDS (0.42)	HSD17B10HPGDALDH1A1PPARGHRH3
	SCHEMBL14715019	0.81	HRH3 (0.42)	HSD17B10HPGDALDH1A1PPARGHRH3
	SCHEMBL14715383	0.81	PPARG (0.40)	NPC1RAB9ATP53SMN1; SMN2ALDH1A1
	SCHEMBL14714737	0.81	KLKB1 (0.51)	NPC1RAB9AHPGDKLKB1ROCK2
	SCHEMBL14715222	0.81	PPARG (0.39)	HSD17B10HPGDALDH1A1PPARGHRH3
	SCHEMBL14715425	0.81	PPARG (0.50)	PPARGHRH3
	SCHEMBL14714981	0.80	ANPEP (0.49)	NPC1PPARGHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.