SCHEMBL14715019

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14714539	0.85	HPGDS (0.42)	HRH3HPGDSPPARGALDH1A1TBXAS1
	SCHEMBL14714513	0.83	HRH3 (0.42)	HRH3PPARGEGLN2ALDH1A1HSD17B10
	SCHEMBL14715228	0.82	HRH3 (0.41)	HRH3PPARGTBXAS1
	SCHEMBL14715017	0.82	HPGD (0.55)	ALDH1A1HPGDHSD17B10MAPK14
	SCHEMBL14715049	0.82	PPARG (0.51)	HRH3PPARG
	SCHEMBL14715334	0.81	CHRNB2 (0.43)	HRH3PPARGALDH1A1HPGDHSD17B10
	SCHEMBL14715281	0.81	HRH3 (0.42)	HRH3HPGDSPPARGTBXAS1
	SCHEMBL14715222	0.81	PPARG (0.39)	HRH3PPARGALDH1A1HPGDHSD17B10
	SCHEMBL14715425	0.81	PPARG (0.50)	HRH3PPARG
	SCHEMBL14715050	0.81	NPC1 (0.41)	HRH3PPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.