Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.47 |
| ▸ | DRD3 | P35462 | 12/20 | 0.47 |
| ▸ | GPR6 | P46095 | 3/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078171 | 0.88 | DRD2 (0.54) | DRD2DRD3PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL14715595 | 0.88 | DRD2 (0.44) | DRD2DRD3 | |
| SCHEMBL3959409 | 0.81 | GPR6 (0.44) | DRD2DRD3GPR6 | |
| SCHEMBL14715573 | 0.80 | DRD2 (0.49) | DRD2DRD3 | |
| SCHEMBL14715656 | 0.79 | DRD2 (0.53) | DRD2DRD3 | |
| SCHEMBL14715744 | 0.77 | HRH3 (0.44) | GPR6 | |
| SCHEMBL3075391 | 0.77 | HRH3 (0.44) | GPR6 | |
| SCHEMBL3084647 | 0.76 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL3082997 | 0.75 | DRD2 (0.60) | DRD2DRD3 | |
| SCHEMBL4991586 | 0.74 | DRD2 (0.64) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079693-B1 | ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |