Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452860 | 0.88 | MET (0.40) | MET | |
| SCHEMBL2528823 | 0.87 | MET (0.38) | METMAPT | |
| SCHEMBL14715596 | 0.85 | MET (0.40) | MET | |
| SCHEMBL14715539 | 0.85 | MET (0.39) | MET | |
| SCHEMBL12224215 | 0.81 | MET (0.46) | MET | |
| SCHEMBL12224224 | 0.79 | MET (0.38) | METMAPT | |
| SCHEMBL14724286 | 0.78 | MET (0.38) | METMAPT | |
| SCHEMBL2458149 | 0.77 | MET (0.44) | MET | |
| SCHEMBL2531125 | 0.77 | MET (0.42) | MET | |
| SCHEMBL2529534 | 0.76 | MET (0.45) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367827-B1 | 3-(3-PYRIMIDINE-2-YL-BENZYL)-[1,2,4]TRIAZOLO [4,3-b]PYRIDAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-02-27 | — | — | EP | claimed |