Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 13/20 | 0.48 |
| ▸ | DRD3 | P35462 | 11/20 | 0.48 |
| ▸ | HTR2A | P28223 | 10/20 | 0.48 |
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715677 | 0.92 | AR (0.52) | ARDRD2DRD3HTR2AHTR1A | |
| SCHEMBL3087616 | 0.89 | DRD3 (0.61) | ARDRD2DRD3HTR2AHTR1A | |
| SCHEMBL14715648 | 0.89 | DRD2 (0.44) | ARDRD2DRD3HTR2AHTR1A | |
| SCHEMBL14715723 | 0.89 | DRD2 (0.44) | ARDRD2DRD3HTR2AHTR1A | |
| SCHEMBL14715633 | 0.88 | AR (0.48) | ARDRD2DRD3HTR2AHTR1A | |
| SCHEMBL14715628 | 0.86 | DRD2 (0.49) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL14715630 | 0.84 | DRD2 (0.51) | ARDRD2DRD3HTR2AHTR1A | |
| SCHEMBL14715692 | 0.83 | DRD2 (0.49) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL3086163 | 0.81 | DRD3 (0.59) | ARDRD2DRD3HTR2AHTR1A | |
| SCHEMBL27882701 | 0.81 | HRH1 (0.47) | DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079693-B1 | ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |