Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.49 |
| ▸ | DRD3 | P35462 | 14/20 | 0.49 |
| ▸ | HTR2A | P28223 | 11/20 | 0.49 |
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715633 | 0.92 | AR (0.48) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL14715628 | 0.88 | DRD2 (0.49) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL3073465 | 0.87 | DRD3 (0.64) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL14715630 | 0.85 | DRD2 (0.51) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL14715677 | 0.85 | AR (0.52) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL14715599 | 0.83 | AR (0.51) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL3083219 | 0.79 | DRD3 (0.62) | DRD2DRD3HTR2AHTR1ADRD4 | |
| SCHEMBL15911282 | 0.78 | DRD2 (0.77) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL15911212 | 0.76 | DRD2 (0.78) | DRD2DRD3HTR2A | |
| SCHEMBL3089494 | 0.76 | DRD3 (0.64) | DRD2DRD3HTR2AHTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079693-B1 | ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |