Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960275 | 1.00 | FPR2 (0.47) | FPR2PROKR1EPHX2ALDH1A1POLB | |
| SCHEMBL3965016 | 0.91 | FPR2 (0.46) | FPR2PROKR1EPHX2TBK1HRH1 | |
| SCHEMBL3079707 | 0.88 | HRH1 (0.44) | ALDH1A1HRH1DRD3CCR3KCNH2 | |
| SCHEMBL14715627 | 0.88 | HRH1 (0.44) | ALDH1A1HRH1DRD3CCR3KCNH2 | |
| SCHEMBL3084815 | 0.88 | DRD3 (0.52) | FPR2PROKR1EPHX2HTR2ADRD3 | |
| SCHEMBL3960280 | 0.88 | FPR2 (0.47) | FPR2PROKR1EPHX2TBK1HRH1 | |
| SCHEMBL14715698 | 0.88 | FPR2 (0.47) | FPR2PROKR1EPHX2TBK1HRH1 | |
| Hydrochloric Acid SCHEMBL3074546 | 0.87 | FPR2 (0.46) | FPR2PROKR1EPHX2TBK1HRH1 | |
| SCHEMBL3959472 | 0.87 | MEN1 (0.46) | EPHX2ALDH1A1HTR2ADRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL3074547 | 0.87 | FPR2 (0.46) | FPR2PROKR1EPHX2TBK1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079693-B1 | ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |