Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 19/20 | 0.54 |
| ▸ | HRH1 | P35367 | 18/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965013 | 1.00 | CCR3 (0.54) | CCR3HRH1KCNH2 | |
| SCHEMBL14715736 | 0.85 | HRH1 (0.50) | CCR3HRH1KCNH2 | |
| SCHEMBL14715703 | 0.85 | HRH1 (0.50) | CCR3HRH1KCNH2 | |
| SCHEMBL3969152 | 0.83 | NAMPT (0.48) | CCR3HRH1 | |
| SCHEMBL14715740 | 0.83 | DRD2 (0.47) | — | |
| SCHEMBL14715680 | 0.83 | NAMPT (0.48) | CCR3HRH1 | |
| SCHEMBL3084998 | 0.81 | NAMPT (0.55) | — | |
| SCHEMBL3085000 | 0.81 | NAMPT (0.55) | — | |
| SCHEMBL14715670 | 0.81 | HRH1 (0.47) | CCR3HRH1KCNH2 | |
| SCHEMBL3956550 | 0.81 | HRH1 (0.47) | CCR3HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079693-B1 | ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |