Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 17/20 | 0.50 |
| ▸ | CCR3 | P51677 | 17/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715703 | 1.00 | HRH1 (0.50) | HRH1CCR3KDM4EKCNH2DRD2 | |
| SCHEMBL14715735 | 0.85 | CCR3 (0.54) | HRH1CCR3KCNH2 | |
| SCHEMBL3965013 | 0.85 | CCR3 (0.54) | HRH1CCR3KCNH2 | |
| SCHEMBL5369447 | 0.82 | HRH1 (0.56) | HRH1CCR3KDM4EKCNH2 | |
| SCHEMBL3067858 | 0.81 | HTR7 (0.46) | DRD2 | |
| SCHEMBL3067860 | 0.81 | HTR7 (0.46) | DRD2 | |
| SCHEMBL2923912 | 0.80 | HRH1 (0.52) | HRH1CCR3KDM4EKCNH2 | |
| SCHEMBL14715741 | 0.80 | DRD2 (0.59) | HRH1KCNH2DRD2 | |
| SCHEMBL5102799 | 0.80 | HRH1 (0.59) | HRH1CCR3KDM4EKCNH2 | |
| SCHEMBL3085004 | 0.79 | NAMPT (0.52) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079693-B1 | ETHER DERIVATIVES DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2013-02-27 | — | — | EP | claimed |