Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421931 | 0.86 | CALM1 (0.48) | CALM1 | |
| SCHEMBL4632216 | 0.71 | CALM1 (0.52) | CALM1BCL2BCL2L1LMNATSHR | |
| Diphenylmethane SCHEMBL28172316 | 0.68 | CALM1 (1.00) | CALM1LTA4HBCL2BCL2L1LMNA | |
| Diphenylmethane SCHEMBL4361124 | 0.68 | CALM1 (1.00) | CALM1LTA4HBCL2BCL2L1LMNA | |
| Diphenylmethane SCHEMBL1303 | 0.68 | CALM1 (1.00) | CALM1LTA4HBCL2BCL2L1LMNA | |
| Diphenylmethane SCHEMBL14763944 | 0.68 | CALM1 (1.00) | CALM1LTA4HBCL2BCL2L1LMNA | |
| Diphenylmethane SCHEMBL3792579 | 0.68 | CALM1 (1.00) | CALM1LTA4HBCL2BCL2L1LMNA | |
| Diphenylmethane SCHEMBL28072604 | 0.66 | CALM1 (0.80) | CALM1LTA4HBCL2BCL2L1LMNA | |
| Diphenylmethane SCHEMBL28085719 | 0.66 | CALM1 (0.80) | CALM1LTA4HBCL2BCL2L1LMNA | |
| Diphenylmethane SCHEMBL25403056 | 0.65 | CALM1 (0.92) | CALM1LTA4HBCL2BCL2L1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3995492-B1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | SpecGx LLC (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-3166923-B1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | SpecGx LLC (US) | 2023-03-15 | — | — | EP | disclosed |
| EP-3995492-A1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | SpecGx LLC (US) | 2022-05-11 | — | — | EP | disclosed |
| EP-3319941-B1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | SpecGx LLC (US) | 2021-12-29 | — | — | EP | disclosed |
| EP-3319941-A1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | SpecGx, LLC (US) | 2018-05-16 | — | — | EP | disclosed |
| US-9914695-B2 | Two-step process for preparing 3-substituted phenylalkylamines | MALLINCKRODT LLC (US) | 2018-03-13 | — | — | US | disclosed |
| EP-3166923-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | Mallinckrodt LLC (US) | 2017-05-17 | — | — | EP | disclosed |
| US-9556108-B2 | Process for preparing substituted phenylalkanes | MALLINCKRODT LLC (US) | 2017-01-31 | — | — | US | disclosed |
| WO-2017011231-A1 | A TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | MALLINCKRODT LLC (US) | 2017-01-19 | — | — | WO | disclosed |
| EP-2533644-B1 | DIAZENIUMDIOLATE CYCLOPENTYL DERIVATIVES | MERCK SHARP & DOHME (US) | 2017-01-18 | — | — | EP | disclosed |
| US-20170008832-A1 | TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | MALLINCKRODT ENTERPRISES LLC | 2017-01-12 | — | — | US | disclosed |
| US-20160009635-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY | 2016-01-14 | — | — | US | disclosed |
| WO-2016007823-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | MALLINCKRODT LLC (US) | 2016-01-14 | — | — | WO | disclosed |
| US-8648058-B2 | Diazeniumdiolate cyclopentyl derivatives | MERCK SHARP & DOHME CORP. (US) | 2014-02-11 | — | — | US | disclosed |
| US-20130053352-A1 | DIAZENIUMDIOLATE CYCLOPENTYL DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009635-A1 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | CYP2E1, CYP1B1, CYP4B1 | CALM1 4108/4885LTA4H 654/4885BCL2 1785/4885 |
| US-20170008832-A1 | TWO-STEP PROCESS FOR PREPARING 3-SUBSTITUTED PHENYLALKYLAMINES | PNMT, CYP1B1, UGT2B7 | CALM1 3936/4885LTA4H 3149/4885BCL2 1678/4885 |
| US-20130053352-A1 | DIAZENIUMDIOLATE CYCLOPENTYL DERIVATIVES | OR10J3, OXSR1, OXER1 | CALM1 3364/4885LTA4H 3735/4885BCL2 3408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.