SCHEMBL14717610

SCHEMBL14717610

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)N(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.35
CA2 P00918 3/20 0.35
CA1 P00915 2/20 0.35
MMP1 P03956 2/20 0.35
MMP2 P08253 2/20 0.35
MMP9 P14780 2/20 0.35
MMP8 P22894 2/20 0.35
MMP13 P45452 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11421524 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL78572 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL195985 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL17111382 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL480135 1.00 LMNA (0.42) LMNATHRBCA2CA1MMP1
SCHEMBL36219 0.96 LMNA (0.37) LMNATHRBCA2CA1MMP1
SCHEMBL7560330 0.94 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL7563577 0.94 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL7796380 0.94 LMNA (0.38) LMNATHRBCA2CA1MMP1
SCHEMBL9546264 0.93 LMNA (0.35) LMNACA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130052309-A1 OXYGEN EMITTERS IN PACKAGED MEAT PRODUCTS SARA LEE CORPORATION 2013-02-28 US disclosed