Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421524 | 1.00 | LMNA (0.42) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL14717610 | 1.00 | LMNA (0.42) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL78572 | 1.00 | LMNA (0.42) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL195985 | 1.00 | LMNA (0.42) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL17111382 | 1.00 | LMNA (0.42) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL36219 | 0.96 | LMNA (0.37) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL7560330 | 0.94 | LMNA (0.38) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL7563577 | 0.94 | LMNA (0.38) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL7796380 | 0.94 | LMNA (0.38) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL9546264 | 0.93 | LMNA (0.35) | LMNACA2CA1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412020-B1 | SLIP CHIP DEVICE AND METHODS | UNIV CHICAGO (US) | 2020-09-30 | — | — | EP | disclosed |
| US-10543485-B2 | Slip chip device and methods | UNIVERSITY OF CHICAGO (US) | 2020-01-28 | — | — | US | disclosed |
| US-20160288121-A1 | Slip Chip Device and Methods | THE UNIVERSITY OF CHICAGO | 2016-10-06 | — | — | US | disclosed |
| US-20160256870-A1 | Slip Chip Device and Methods | UNIVERSITY OF CHICAGO | 2016-09-08 | — | — | US | disclosed |
| US-9415392-B2 | Slip chip device and methods | THE UNIVERSITY OF CHICAGO (US) | 2016-08-16 | — | — | US | disclosed |
| US-20120028342-A1 | SLIP CHIP DEVICE AND METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-02 | — | — | US | disclosed |
| EP-2412020-A1 | SLIP CHIP DEVICE AND METHODS | University Of Chicago (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111265-A1 | SLIP CHIP DEVICE AND METHODS | UNIVERSITY OF CHICAGO (US) | 2010-09-30 | — | — | WO | disclosed |